I am not using topa but have found Calms very useful at night. I take 3 before bed and even though my consumption has been so much less I am still sleeping well. This morning I woke after a fitful night and realized I skipped it last night. I took 2 about 5:00 this morning and I found them very calming. I am tired, but I really feel it is from the lack of sleep rather than the calms. IO think they just help you feel mellow.
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