[Isolde]

Hey there sashha and skempy! I was also VERY concerned about the fatigue from Topa. I tend to be naturally kind of tired during the day (I blame it on sitting in front of a computer for 8 hours at work), so being MORE tired AND kind of dopey was not something I was looking forward to. The first day I did feel like I was very sleepy, much more so than usual. The second day was not as bad though. And really it has not been bad at all since then. Some periods of tiredness here and there, but that is really pretty normal for me. I do the normal split - one dose in the am, and then the second about 12 hours later. The last couple of days I've actually felt kind of energized, almost jittery. In a good way! I didn't even think about it until I started typing this post, but I am taking another supplement that is not on the MWO list. I've been taking it on and off for a few years, and just recently started it up again. And I have noticed that when I've ramped up the dosage in the past, I have felt more energized and alive. So maybe that is why I am not feeling so tired and goofy from the Topa. I couldn't say for sure of course, but it is an outside variable that could be a factor. The supplement is MSM. You can google it if you're interested in reading more about it - it has tons of benefits. I am currently taking 8 grams a day in powder form (you have to ramp up slowly, as it can cause some GI upset).

Today is my 7th day on 50mg of Topa, so I'm bumping up to 75mg tomorrow. So far I'm doing well! Cravings are definitely reduced, both for alcohol and food! It changes the way that a lot of drinks taste - anything carbonated, so there goes my beer and all the mixers I use for my mixed drinks! I think that plays a role in craving reduction right there.

I do feel kind of headachey pretty often, just slight though. Not sure if it's strictly from the Topa, or an interaction between that and the MSM. It's not enough to make me reach for the Advil or anything, but it gets worse when I drink. I am drinking a LOT of water and always feeling like I need more.

In any case, even if the MSM is the only thing keeping me from passing out on my keyboard at work during the day, I have read a lot of posts that say the effects DO go away after about a month or so. My doc said the same thing as well. So just be prepared with extra coffee/tea/energy drinks for a bit! I also ordered the Adrafinil the same day I got my Topa script, but by the time it gets to me I will have supposedly gotten over the 1 month hump anyway!

Best of luck to both of you! Keep us posted on how you're doing!