Nancy..I actually have taken Naltrexone (oral) a few times. It did work for me for a little bit, but it's easy to "forget" to take it or let the craving get to you and then it's too late. I did take it a few times when I first started because i wanted the reassurance, but honestly, I haven't had to take it since the first or second day. The supplements seem to take care of the urge. Also, there were times when I took it and drank anyway..talk about a hangover..yuk..sick, really sick, laying on the bathroom floor praying for death sick...my dr. seemed to think this was an unusual reaction, but after some research I found that this can be one of the side effects. It lowers your tolerance and is supposed to take the euphoria out of alcohol. Anyway, I guess like anything it is a mind set. Naltrexone may be something to hold you over until you can get the topa or at least until you can make the supps a consistent habbit. Read about it and discuss it w/ your dr. It's not the miracle cure they thought it was a few years back, but it definitely is a support mechanism..at least it was for me.good luck..and let us know..SD