PG,
I am not a doctor BUT there are several people here who have been on Topamax for a long, long time and staying sober.
I hope they post and respond here.
Also, Topamax is an anti-seizure medication. People who suffer from seizures take Topamax forever.
While I am not versed in the effects of taking it long term, I can say that there are those who have no choice.
It is great to hear it is helping you so much!! Congratulations and

to MWO.
Cindi