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  #21 (permalink)  
Old 08-31-2010, 08:33 PM
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I have used melatonin with good results at times. Teas tend to upset my stomach worse than alcohol! I have also used benadryl but If I take it too late I am sort of loggy in the morning.
I am still at 15 and doing fine. This is a good thread
Sunny
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  #22 (permalink)  
Old 09-05-2010, 09:14 AM
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Default tapering down too quickly (of necessity)

hi there I nave followed much of the information with great interest. My present situation is that I titrated up to 275mg of baclofen and stayed there for 6 weeks. i was difficult but not impossible. I didnt reach the switch on reaching this level but did reach it after a month. I stayed there for another 2 weeks because I was risk-aversive that my immunity to alcohol would dissappear. I then titrated down to 225g - reducing dosage at 12.5 mg every three days. Unfortunately the order I put in for an additional 300 (25mg) tablets for a month had not been processed because I inserted one account detail incorrectly (I didnt check my emails so didint know it had not been processed). Was waiting in vain for the delivery when I did finally check email. Reordered immediately of course. But meanwhile in order to breach the gap between the situation i found myself in that day and ems delivery in 5-7 days' time, I had to come down pretty drastically to 125mg eak out my remaining supply.

The effects of this drastic reduction has been the same as those experienced by another member:

neck pain
muscle pain
anxiety and fear
panic
general overflood of feelings, leaves me sometimes a bit paralyzed

This member suggests that the body needs to have enough time to compensate the reduced GABA activity by starting its own activity again.

My question is: do I tritrate back up to 225mg in order to give my body enough time to replenish the GABA activity that was severely curtailed with the above unpleasant effects? And then tritrate slowly down to 125mg which was to be my long-term target?

Or do I stay at 125mg now?

The anxiety is the worst thing - the kind of thing I used to get frequently after a bout of heavy drinking. It leads one to speculate all kinds of nightmares - in particular that with my carelessness I have undermined and undone all the good work that has been done with this amazing treatment.
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  #23 (permalink)  
Old 09-05-2010, 09:53 AM
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hi henry,

When I jumped from 250mg to 150mg I had the following day craving, so I upped the dose back up. Luckily I had enough pills.

The higher you are up the faster you can go down with the dose. I used to do minus 15mg every 4 days which worked well.

Since you have been on the lower dose for some time now, I would not go back to 225mg, but instead I would try to up the dose from where you are now.
Going to 150 or 175mg / day may stop your anxiety within 3-4 days. Then stay on the comfortable dose for some time until your body is in balance again, and then I would start a titration down shedule with 12.5 - 15mg down every 4 days until reaching your goal of 125mg. Doing this temporary upping and then lowering slowly will give your body more time to compensate and you will feel a lot better with the lower dose later on then.

Because you are on a lower dose already your body was forced to start part of its GABA activity in an "emergency" program. Going back to 225mg would make your body again stop part of its activity again.

Simply go up slowly again to the point where the anxiety disappears, once you are there you will be able to think very clearly again.
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since 23. Apr 2009 : TSM - failed to reduce units
since 08. Jan 2010 : Naltrexone + Baclofen combination therapy
reborn since 16. Jan 2010 : Alcohol Free (AF) - only taking Baclofen
since 22. May 2010 : Baclofen against anxiety/fear
since 14. Mar 2011 : off Baclofen - taking 25mg Topamax/day

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  #24 (permalink)  
Old 09-05-2010, 11:57 AM
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thanks for this. much appreciated. i have in fact only been on the 125mg dosage for 6 days but I suppose this is sufficient time so your advice is well taken. coming down from 225 to 125 in one day has been pretty hard on me. i still havent received my supply as of yet and will run out after tuesday. my supply was shipped thursday. given 5-9 working days on EMS express delivery the earliest i can expect is this coming wednesday. the latest could be the tuesday after - in which case i would be baclofen-free for 6 days. Not a prospect i look forward to.
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  #25 (permalink)  
Old 09-05-2010, 01:05 PM
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In no way should you run out of Baclofen, the 225mg -> 125mg will then look like piece of cake in my opinion.

On high dose it is very easy to reduce, on lower dose the body needs significantly more time to adjust or the side effects can be unbearable.
If you can't get your Baclofen in time I suggest finding a doctor to prescribe it to you. Even if he does not agree to your treatment he needs to help you titrating down.

Baclofen can be best compared to Benzos in the way it needs to be titrated down. Benzos you would also titrate down in big steps first, and then for the last few steps you would lower it even slower over even bigger time intervals.

My guess is that the body can re-activate a big portion of the GABA activity in a matter of days. But the rest is more slow and if you take away the stimulating GABA activity of Baclofen, your body won't be able to run the emergency program as good and fast as it was trying with lowering the dose.

All the best. I hope it comes in time!
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since 23. Apr 2009 : TSM - failed to reduce units
since 08. Jan 2010 : Naltrexone + Baclofen combination therapy
reborn since 16. Jan 2010 : Alcohol Free (AF) - only taking Baclofen
since 22. May 2010 : Baclofen against anxiety/fear
since 14. Mar 2011 : off Baclofen - taking 25mg Topamax/day

My stats :
http://www.baclofen-forum.com/stats/craving/
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  #26 (permalink)  
Old 09-05-2010, 05:11 PM
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Henry, I would suggest that you avoid complete withdrawal by decreasing your current dose to make it last until the Rx comes. I know that would result in worse symptoms but would avoid the going to zero. You may also be able to go to your doctor and advise him/her of the situation and get an emergency script for this situation.
If you live in the US I could mail you some pills on Tuesday to tide you over for a few days. PM me if interested.
Sunny
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  #27 (permalink)  
Old 09-06-2010, 11:13 AM
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thankyou for your kind offer. I have checked the tracking number of my mail and it says that it left the host country on friday so here's hoping! I will tritrate down to 50mg a day I think in order to avoid having szero tablets for a number of days. it is better than the alternative i think! thanks again.
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  #28 (permalink)  
Old 09-06-2010, 11:15 AM
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when i said thankyou for your kind offer i meant it .... i should have said that i live in the Uk. thanks again.
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  #29 (permalink)  
Old 09-06-2010, 02:24 PM
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You are welcome. I now am down to 15 mg/day with no cravings or withdrawal symptoms. I am just thrilled that this med seems to be working so well. Hope your supply comes in soon. I agree w craving that once you get your supply go up slowly until the symptoms abate then stay there several days at least to "normalize" then decide if it is time to taper down. I can't recall, how long have you been AF?
sunny
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  #30 (permalink)  
Old 09-14-2010, 05:58 AM
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I have made another attempt at tapering down further.

Reminder: hit the switch at 270mg in August 2009, have been at 80mg for (more or less) 9 months now after titrating down. When going below 60, I remain indifferent to alcohol (I have deliberately made an effort to test that by browsing wine shelves in shops etc. BUT: I do feel somewhat anxious at that level.

I am now going to stay on 80 indefinitely. I have absolutely no SEs, and it works for me.
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