Couple questions on titrating off at 120 mg/day and nootropics

[haltme]

@Mom2JTx3 - this thread use of Fasoracetam in conjunction with Baclofen, may help with memory / amnesia got me interested in Fasoracetam. It apparently helps with baclofen memory lapses.

Piracetam needs to be taken with a choline source, just FYI! I found that when I took it, I felt much sharper.

@_serenity_, You're saying Fasoracetam works well with Baclofen? It doesn't combat the effectiveness or absorption of Baclofen?

[_serenity_]

@haltme, *I* am not saying that! The post that I linked had a quote that said that fasoracetam could possibly block the memory lapses. Bac has long played havoc with my short-term memory. I have thought about experimenting with fasoracetam to see it it helped.

[havaro]

Sorry to bring back an old thread to life, but has anybody of you tried actually use fasoracetam to taper down baclofen? And how was it?


Thank you very much!

[georgesmiley]

@_serenity_ ,

I'm curious about the memory issues. I'd felt some possibly similar feelings - but never put it together with baclofen.

So I asked professor google, and while there are many 'thoughts' out there, much of the proper research I found* suggested no or negligible impact.

What are your thoughts? Experiences? (Assuming you can remember them...)

George Smiley

*On tiny groups of humans (eg n=5) or rats, so make of it what you will.

[_serenity_]

Hi @georgesmiley,

It's pretty common for people who are titrating up on baclofen, or who are on higher doses of baclofen, to have memory issues. I remember way back in 2010 when I was titrating up, I was told on here to make a plan for my doses because I would get to the point where I'd forget whether I'd taken it yet, how much I'd taken etc. I was told to set phone alarms or to divide up my daily doses in advance so I wouldn't forget to take them. And I definitely noticed issues with my memory, especially at my switch dose (190 mgs/day). That was a large reason why I wanted to taper down after reaching indifference (which I did and promptly relapsed--it took some time for me to find a happy medium). To this day, I put my baclofen into one of those "day of the week" pill boxes. A few years ago I went through a phase in which I took my entire dosage once a day (I do not recommend this and don't do it anymore). I believe I was taking 140 mgs/day. One day I took my pills, forgot about it, and took 140 mgs a second time. I got so sick. Baclofen ODs are no fun...

Odd that the studies haven't showed a link, because it was a common side effect and was widely reported around these parts. I wouldn't call what I experienced memory loss, it was more like memory lapses. But they were very noticeable.

[georgesmiley]

That's excellent, @_serenity_ - as ever.

It's just so valuable to have experiences. And 'studies' = rats + 5 humans, as far as I can tell. I suppose the real issue is that the scientific/medical community refuses to engage with the doses of baclofen that we use.

May I ask a personal question? No obligation to answer it. When you relapsed, did you go back to being a daily drunk? Or to drinking more than zero, or more than you wanted, but not as much as before? As I said, no requirement to answer! Thank you, as always, for your thoughts.