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    #1

    Anyone on Selincro? (nalmefene)

    Hi guys new to this site as a registered user. Have been takin 80mg of prescribed bac for 2 years now. Last few months its not been holdin me and have been on many benders from fridays to mondays cost me a lot of money physical and mental pain and missed a lot of work. Been back in touch with the good dr.chick and he has wrote me a script for nalmefene. Going to tak to pharmacy tomorrow and give this a try i dont feel ready to be AF and was going to try just moderation and from what iv read this is ideal.

    So just wondered if any one on here has been using it with what success etc. Also if anyone has links to interestin articles about it that would be appreciated. Read all the usual about it.

    Cheers.
    Tags: None
    #2
    Anyone on Selincro? (nalmefene)

    Selincro

    Hi

    I wondered how you're getting on with selincro?
    I saw Chick in August and have been on 80mg baclofen for about 6 weeks but it's not working for me and I'm back drinking 2.5 bottles of wine 3-4 nights a week.
    Thinking I might ask him for selincro when I see him next week and see If it helps. He gave me the booklet last time but I thought I wanted abstinence but now I've got no idea.

    Thanks,

    Poppy :new:

    Comment

      #3
      Anyone on Selincro? (nalmefene)

      Has anyone any idea how much its cost all in from first consultation to getting the meds? I'm in the UK but a good few miles from Edinburgh.

      Comment

        #4
        Anyone on Selincro? (nalmefene)

        I think you should try bac at higher levels than Dr. Chick prescribes and also look at taking Mirtazapine. My wife saw Dr. Chick and he refused to go over 100 mg and we had to get help from a doctor in Paisley. There were lots of benders throught the first few "years" on the baclofen and they only stopped when my wife got a prescription for Mirtazapine which she takes with the baclofen. That was the missing link and the problem with Dr. Chick is that he is very conservative in his approach, tends to see only middle class types who have moderate drink problems, recommends AA, doesn't take a comprehensive history, doesn't look at other issues such as brain trauma and doesn't try to combine baclofen with other drugs. Much as I respect him for supporting baclofen, you need to go further than he is prepared to go. The other doctor we saw deals with more severe cases and said that Dr. Chick does not deal with serious alcoholism cases. mainly high functioning professionals who can pay his fees and live near Edinburgh. PM me. We had three NHS doctors prescribing Baclofen in Glasgow and area.
        BACLOFENISTA

        baclofenuk.com

        http://www.theendofmyaddiction.org





        Olivier Ameisen

        In addiction, suppression of symptoms should suppress the disease altogether since addiction is, as he observed, a "symptom-driven disease". Of all "anticraving medications used in animals, only one - baclofen - has the unique property of suppressing the motivation to consume cocaine, heroin, alcohol, nicotine and d-amphetamine"

        Comment

          #5
          Anyone on Selincro? (nalmefene)

          I've had great success with Naltrexone which was the old version of nalfeme. This was prescribed for me by Dr Chick after he gave me his opinion which was that baclofen wouldn't work for me - I'd already gone to a fairly high dose and suffered greatly from side effects.

          Using Naltrexone as per TSM enabled me to kill the cravings which had meant I was hopelessly addicted to alcohol and get back in control of my life.

          Some might say because I wasn't a daily drinker all the time that I wasn't alcoholic.

          Anyone who knew me personally, knew the time I had to take from work, jobs I lost, vomiting for 12 hours after a bender, things I did which still have impact on my life today, complete and utter disregard for my own or anyone else's well being and inability to not pour 30 units in 4 hours down my neck would definitely say I was alcoholic. I've also taken alcohol which wasn't mine, hidden bottles and been in black out too may times to remember. I thought about alcohol daily and would fend off the cravings until I gave in which could be the same day, or in 3 days time.

          The Sinclair method changed all of this, immediately my alcohol intake more or less halved, and once the cravings were eliminated (6 months in)I spent 2 years moderating with TSM (which to me was a successful trade off) before finally decided I no longer liked even one drink and going AF almost 3 month ago.

          Nalfeme is supposed to be a much better formulation, more effective, less side effects than Naltrexone. If you feel it's going to give you the results you want, give it a go.

          I liked the fact you don't have to take it if you aren't drinking - so if you do have AF days there's no meds involved on those days. I occasionally take Nal to try combat a binge eating issue I have developed with chocolate, but aside from that the cravings for alcohol haven't returned in 3 months of not consuming alcohol or regular use of naltrexone. It's fabulous and I hope it stays that way.

          You may wish to read my Sinclair Method thread which should be somewhere below this one.
          I used the Sinclair Method to beat my alcoholic drinking.

          Drank within safe limits for almost 2 years

          AF date 22/07/13

          Comment

            #6
            Anyone on Selincro? (nalmefene)

            So you're saying that Naltrexone worked for you - not Nalmefene ?

            Is there a thread anywhere on here by persons who have experience of Nalmefene ?

            [ Baclofen did nothing whatever for me.]

            Comment

              #7
              Anyone on Selincro? (nalmefene)

              riv;1680974 wrote: So you're saying that Naltrexone worked for you - not Nalmefene ?

              Is there a thread anywhere on here by persons who have experience of Nalmefene ?

              [ Baclofen did nothing whatever for me.]
              Yes.

              When I started TSM Nalmefene was not available, hadn't been released yet so I used Naltrexone.

              Whilst I cannot comment on Nalmefene, I have read that it's an improved version of Naltrexone, specifically developed for TSM/use with alcoholism. I would therefore guess that if Naltrexone worked well for me that Nalmefene could be even better. My GP asked me if I'd like to switch to the new drug but we decided (a) why switch when I was happy with naltrexone, TSM had removed my cravings to the point where I rarely drank and (b) not long after nalmefene was released I decided to go totally AF and so do not need to take either medication because for me it's done it's stuff and if you don't drink, you don't take it.
              I used the Sinclair Method to beat my alcoholic drinking.

              Drank within safe limits for almost 2 years

              AF date 22/07/13

              Comment

                #8
                Anyone on Selincro? (nalmefene)

                Thanks for this.
                Do you know if Nalmefene works in a different way, chemically, to Baclofen?
                I ask because as Baclofen had zero effect on my cravings for alcohol, unless Nalmefene works differently I suspect it would not counter the cravings .
                I can't find anyone with actual experiences of Nalmefene on this site.

                Comment

                  #9
                  Anyone on Selincro? (nalmefene)

                  riv;1681124 wrote: Thanks for this.
                  Do you know if Nalmefene works in a different way, chemically, to Baclofen?
                  I ask because as Baclofen had zero effect on my cravings for alcohol, unless Nalmefene works differently I suspect it would not counter the cravings .
                  I can't find anyone with actual experiences of Nalmefene on this site.
                  I take it you've not read anything on TSM or Naltrexone?

                  I'll fill you in on Naltrexone, Nalfemene and naltrexone are virtually the same thing, it's just an improved formula.

                  Naltrexone DOES NOT work on the same system as Baclofen.

                  Naltrexone is an opiod blocker.

                  Some people use Naltrexone with abstenance and find it removed cravings however the most effective way to use it(and Nalmefene) is as per The Sinclair Method (TSM).

                  Endorphins are the body's natural opiods.

                  Endorphins are released when you drink alcohol.

                  Some people's drinking is driven by the endorphins released.

                  In TSM you take 50mg Naltrexone 1 hour before drinking alcohol. The naltrexone blocks any endorphins released. The dose is fixed at the amount required to cover all the opiod receptors, ie once at optimum dose, there's no benefit in taking any more. Some people find 25mg is enough, others 100mg. Side effects such as nausea are reduced by cutting the dose and titrating up to 50mg - but this side effect is supposedly less with Nalmefene.

                  Over time, with continued use, many who try TSM find their desire to drink drops away, they can say no, and put the drink down sooner. Finally after 6-12 months of continued use their cravings for alcohol go completely and they can then either drink within safe limits, or quit alcohol without much if any effort.

                  Baclofen works on a different system, in a different way.

                  With naltrexone you only take it when you drink.

                  Took 6 months to work completely for me, but my intake halved from my first drinking session on naltrexone.

                  I tried Baclofen before Naltrexone and it didn't work for me. Naltrexone did.

                  Nalmefene is designed to have less side effects - naltrexone was originally designed to block opiod drugs such as heroine.

                  TSM = The Sinclair Method you might want to search for those words in google. Whenever Naltrexone is mentioned, Nalmefene works in the same way - just less sides.

                  Sinclair Method - Wikipedia, the free encyclopedia

                  Or you can try a dose of 50mg per day with abstenance.
                  Hope this clears it up for you!
                  I used the Sinclair Method to beat my alcoholic drinking.

                  Drank within safe limits for almost 2 years

                  AF date 22/07/13

                  Comment

                    #10
                    Anyone on Selincro? (nalmefene)

                    Thanks again.
                    Coupla questions:
                    1] I get the theory of how Nalmefene / Naltrexone are supposed to work - but what then is the theory of how Baclofen is supposed to work ( as you say it has a different chemical functional method ) ?;
                    2] Is Nalmefene available on the NHS in England ? ( I gather a month's supply is approx ?100 on private prescrip ). And if it's not avlbl on NHS can an NHS doctor nevertheless issue a script for it and then one pays the private meds price ? Or does one have to visit a private GP to even get the script ?

                    Comment

                      #11
                      Anyone on Selincro? (nalmefene)

                      If you can find a doc who is willing to script nal then I think they would also script you Nalmefene. Its basically just a newer a better form of NAL. Regarding the way in which bac and NAL differ is beyond the scoop of which one post could explain. There's literally tons of info on here and numerous other forums that could fill you in better.

                      Comment

                        #12
                        Anyone on Selincro? (nalmefene)

                        riv;1681773 wrote: Thanks again.
                        Coupla questions:
                        1] I get the theory of how Nalmefene / Naltrexone are supposed to work - but what then is the theory of how Baclofen is supposed to work ( as you say it has a different chemical functional method ) ?;
                        2] Is Nalmefene available on the NHS in England ? ( I gather a month's supply is approx ?100 on private prescrip ). And if it's not avlbl on NHS can an NHS doctor nevertheless issue a script for it and then one pays the private meds price ? Or does one have to visit a private GP to even get the script ?
                        There is loads on in info on this forum about baclofen.

                        In a nutshell it's something to do with GABA and dopamine. Baclofen is thought to reduce the underlying anxiety that drives some people's drinking.

                        Some people use baclofen and Naltrexone/TSM together thus attacking from both angles.

                        Naltrexone is/was approximately ?25-30 for a month's supply on private prescription, Nalmefene is supposedly 2 or 3 times the cost. For me it was definitely worth it because it meant I stopped taking days off (unpaid) work, and the reduction in alcohol consumption. Remember on AF days you don't need to take a tablet, and once you get going with it 'one month's supply' may last 6 weeks or even several months.

                        Some GPs in England prescribe 'off label' on the NHS, especially if you can already show you've made progress (ie privately) and you engage with local alcohol services. In other words, they need proof and other back up to justify it.

                        GPs in Scotland are freely able to prescribe Nalmefene.

                        I am surprised you have used Baclofen without understanding it, but then again also not surprised, many in the general population take 'pills' without understanding what they are, or what they do.
                        I used the Sinclair Method to beat my alcoholic drinking.

                        Drank within safe limits for almost 2 years

                        AF date 22/07/13

                        Comment

                          #13
                          Anyone on Selincro? (nalmefene)

                          I thought Baclofen worked by stopping the 'reward' feelings from drinking and drinking and drinking......
                          Apparently that is how Nalmefene is supposed to work.
                          As at this writing I have managed five nights w/o any alcohol ( after a disastrous Weds night last week with well over two botts of wine plus several gin martinis [ SOOOO delicious !! ] ) .
                          I managed the five nights with the assist two days ago and today of an Antabuse tab from a stash I have from two years ago.
                          present plan is to maybe chalk up a month on wagon using Antabuse as the crutch........and then maybe ask the doc for a scrip for Nalmefene. I don't particularly mind the cost ( lot less than booze anyway ) but I was unsure whether a NHS GP can even presecribe Nalmefene.

                          Comment

                            #14
                            Anyone on Selincro? (nalmefene)

                            riv;1682806 wrote: I thought Baclofen worked by stopping the 'reward' feelings from drinking and drinking and drinking......
                            Apparently that is how Nalmefene is supposed to work.
                            As at this writing I have managed five nights w/o any alcohol ( after a disastrous Weds night last week with well over two botts of wine plus several gin martinis [ SOOOO delicious !! ] ) .
                            I managed the five nights with the assist two days ago and today of an Antabuse tab from a stash I have from two years ago.
                            present plan is to maybe chalk up a month on wagon using Antabuse as the crutch........and then maybe ask the doc for a scrip for Nalmefene. I don't particularly mind the cost ( lot less than booze anyway ) but I was unsure whether a NHS GP can even presecribe Nalmefene.
                            Hope our posts have cleared it up for you.
                            I used the Sinclair Method to beat my alcoholic drinking.

                            Drank within safe limits for almost 2 years

                            AF date 22/07/13

                            Comment

                              #15
                              Anyone on Selincro? (nalmefene)

                              I got my nalfamene from Dr Chick. It works, if you can cope with the nausea and the "spaced out" feeling that it gave me, big time. Good luck.

                              Comment

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