Alternatively to alcohol on the way at last

[Mulburry]

Re: Alternatively to alcohol on the way at last

[MENTION=3640]Mulberry[/MENTION]. My observation is that alcohol is now old-fashioned for the young generation - and they have switched to Cocaine & weed. Much less messy.

Hahahaha. Cocaine is nothing but fuel to keep drinking (at least it was for me).

Cannibis being pretty harmless to be honest, especially if not smoked.

I wouldn't say it's totally harmless, but it's certainly child's play compared to alcohol.

[scotskev81]

Re: Alternatively to alcohol on the way at last

Hahahaha. Cocaine is nothing but fuel to keep drinking (at least it was for me).


I wouldn't say it's totally harmless, but it's certainly child's play compared to alcohol.

Yes I know what you mean. Not totally harmless but not that bad. The smoking of it will be as bad as cigarettes but eating or vaping almost 100% safe by comparison.

[scotskev81]

Re: Alternatively to alcohol on the way at last

GABA – the video – GABALabs

4 min video. Quite interesting

[Mulburry]

Re: Alternatively to alcohol on the way at last

GABA – the video – GABALabs

4 min video. Quite interesting

If you don't have any physical dependance issues with alcohol that might be something to try... for me, I've found an extremely high cross tolerance between alcohol and any gaba-ergic substances, so I'd stay away from it myself.

[techie]

Re: Alternatively to alcohol on the way at last

I take gaba NOW brand. I take two 500mg capsules at bedtime and one in the morning. This had been my routine since my doctor recommended in 2015. I’m not sure about the connection between gaba and alcohol dependence!?

[scotskev81]

Re: Alternatively to alcohol on the way at last

I take gaba NOW brand. I take two 500mg capsules at bedtime and one in the morning. This had been my routine since my doctor recommended in 2015. I’m not sure about the connection between gaba and alcohol dependence!?

How do these gaba NOW pills make you feel?

[techie]

Re: Alternatively to alcohol on the way at last

How do these gaba NOW pills make you feel?

they just calm the nervous system. I’m not aware of any particular sense of them!

[scotskev81]

Re: Alternatively to alcohol on the way at last

they just calm the nervous system. I’m not aware of any particular sense of them!

Thanks. They legal to buy in UK?

[Mulburry]

Re: Alternatively to alcohol on the way at last

I take gaba NOW brand. I take two 500mg capsules at bedtime and one in the morning. This had been my routine since my doctor recommended in 2015. I’m not sure about the connection between gaba and alcohol dependence!?

GABA-A is one of the main neurotransmitters that alcohol effects and the changes in brain chemistry of the GABA system are one the major causes of whithhdrawal symptoms. I was under the impression though, that just taking Gaba supplements would not have much of an effect on the gaba systme in the brain because it does not cross the blood brain barrier easily?

[scotskev81]

Re: Alternatively to alcohol on the way at last

GABA-A is one of the main neurotransmitters that alcohol effects and the changes in brain chemistry of the GABA system are one the major causes of whithhdrawal symptoms. I was under the impression though, that just taking Gaba supplements would not have much of an effect on the gaba systme in the brain because it does not cross the blood brain barrier easily?

No idea about that I'm afraid.

This Sentia had a little effect on me but was very mild.

[Mulburry]

Re: Alternatively to alcohol on the way at last

This Sentia had a little effect on me but was very mild.

Something that affects just GABA won't really give you the "buzz" of drinking though (as Al also effects many other receptors such as dopamine, serotonin, endogenous opiods etc.), it may just have a slightly sedating/calming effect (similar to a very mild version of valium for example). But hey, if it's enough to fool you into thinking you're "drinking", it's better than actually drinking...

[scotskev81]

Re: Alternatively to alcohol on the way at last

Something that affects just GABA won't really give you the "buzz" of drinking though (as Al also effects many other receptors such as dopamine, serotonin, endogenous opiods etc.), it may just have a slightly sedating/calming effect (similar to a very mild version of valium for example). But hey, if it's enough to fool you into thinking you're "drinking", it's better than actually drinking...

Yes that's what I was hoping it would do until the real one comes out in a few years.

[scotskev81]

Re: Alternatively to alcohol on the way at last

Functional Alternatives to Alcohol - PMC

Detailed science document

[scotskev81]

Re: Alternatively to alcohol on the way at last

Co-founder David Orren, out enjoying some SENTIA. ⁠
⁠
David is an internationally-experienced business leader and coach, focussing on companies with disruptive innovation strategies.

From 2016, David has been working to revolutionise the adult social drinking market, working with world-renowned neuropsychopharmacologist, Professor Dave Nutt, to create and bring to market Alcarelle, a novel biomimetic GABAergic compound designed to give adult drinkers what they want from alcohol, without the alcohol

David has developed the business from its biochemical research origins to an organisation ready to take Alcarelle through the US FDA GRAS Dossier process.

En route, David and his team have built a botanical proof-of-concept drinks business, Sentia Spirits, which has taken the market by storm as the only science-based functional beverage currently available. Sentia shows the market what is possible with GABAergic drinks, and sold over 10,000 bottles in Jan 2023, making it the highest performing botanical spirit on Amazon UK.

Alcarelle will go through the FDA regulatory process during 2023 to 2027, entering the US market as an ingredient sold to the Drinks Industry in 2028, then expanding into the EU during 2029, and Japan in 2030.

[scotskev81]

Re: Alternatively to alcohol on the way at last

2027 can't come quick enough. 😭😭